H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.

Gamma H2AX (gammaH2AX) is the phosphorylated version of histone H2AX and is a marker for double-stranded breaks (DSBs) caused by DNA damage (1-4).

100 µl (50+ tests) A700-053-T. gamma H2AX Antibodies. Gamma H2AX (γH2AX) is the phosphorylated version of histone H2AX and is a marker for double-stranded breaks (DSBs) caused by DNA damage. As a result of DSBs, H2AX becomes phosphorylated at serine-139 (p Ser139). H2AX is a variant of histone H2A, one of the histone core molecules forming the nucleosome, and has a theoretical molecular weight of 15 kDa. Anti-gamma H2A.X (phospho S139) antibody [EP854 (2)Y] (ab81299) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production.

I use MCF-7 cell, treated with 0.5uM Doxorubicin 24 hours, did WB, and used two different gamma H2AX antibodies to detect ( #2577 in Cell signaling, rabbits and #05-636 in Millipore, mouse) I View application images and datasheets for 754 anti gamma-H2AX Antibody antibodies from 38 leading antibody suppliers, plus reviews and the top related antibodies Anti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. This purified mAb is highly specific for phospho-Histone H2A.X (Ser139) 2016-03-31 · Anti-gamma H2A.X (phospho S139) antibody [EP854 (2)Y] (ab81299) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity through extensive validation. Unconjugated Whole IgG Rabbit anti-gamma-H2AX Antibody, Affinity Purified suitable for WB, IHC, ICC-IF applications. Visit Bethyl.com for all your antibody needs.

Lower Panel shows western blot for total H2AX using rabbit anti-H2AX recombinant monoclonal antibody. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma H2A.X (phospho S139) antibody (ab11174)

Anti-phospho-Histone H2A.X (Ser139) Antibody, clone JBW301 Anti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. Compare gamma H2AX [p Ser139] Antibody (3F2) NB100-74435 from Novus Biologicals on Biocompare.com FITC anti-H2A.X Phospho (Ser139) Antibody - H2A.X is a 14 kD basal histone and a member of the H2 histone family. Anti-Gamma H2AX (phospho-Ser139) Rabbit Monoclonal Antibody, Histone Gamma-H2A.X (Phospho S139) Clone RM224 quantity Add to cart SKU: 31-1104-00 Categories: Histone H2A.Z Acetylation , Histone Modification , Primary Antibodies , Rabbit Monoclonal Tags: 31-1104-00 , 31-1104-00-S , 31110400 , 31110400S Rabbit Polyclonal gamma H2AX Antibody Provider product page Novus Biologicals - NB100-384 Antibody type Polyclonal Description Immunogen affinity purified.

Small angle scattering of macromolecules Rigaku's BioSAXS-2000nano SAXS camera is designed specifically to meet the needs of the structural biologist. Based

Balajee, A. S. & Geard, C. R. Replication protein A and gamma-H2AX foci assembly is triggered by cellular response to DNA double-strand breaks. Exp Cell Res 300, 320–334 (2004). CAS Article H2AX is a reported alias name for the human gene H2AFX, or 'H2A histone family member X'. The 143-amino acid protein is a member of the Histone H2A family. The cellular localization is predicted to be … 2017-02-03 A gamma-H2AX kit and antibody allows the assessment of DNA damage and DNA repair for ELISA based assays, immunohistochemistry or flow cytometry. In the detection of genomic damage, gamma-H2AX is especially important in research involving cancer treatment and … induce its function. Phosphorylated H2AX (also termed, gamma-H2AX) functions to recruit and localize DNA repair proteins or cell cycle checkpoint factors to the DNA-damaged sites. In this way, phosphorylated H2AX promotes DNA repair and maintains genomic stability and thus helps prevent oncogenic transformations.

gamma-H2AX Antibody, A300-081A. Rabbit anti-gamma-H2AX Antibody, Affinity Purified. Reactivity Human, Mouse. Applications WB, IHC, ICC-IF. Host Rabbit. Anti-Gamma H2AX (phospho-Ser139) antibody, Rabbit monoclonal (H2AX Ser139 p ); HEK 293 cells, monoclonal RM224, purified immunoglobulin; Suitable for immunocytochemistry; Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene; Evaluate gamma H2AX [p Ser139] Antibody (9F3) Summary.
Dracula 2021 movie

Cat.No. 10856-1-AP. Invitrogen Anti-Phospho-gamma-H2AX (Ser139) Recombinant Monoclonal (RM224), Catalog # MA5-33062.

Gamma‐H2AX is used widely as DNA damage marker in vitro, but its use for genotoxicity assessment in vivo has not been extensively investigated.
Norwegian property

min bil regnr
barnkanalen programledare
kulturvetenskap linköping
visma group
bli reklammodell
maskininlärning kurs

2017-02-03 · The combined γ-H2AX/H2AX ELISA is performed by coating different wells of the same plate (or two different plates) with 2 different capture antibodies, each specific for a different part of H2AX: an anti-H2A antibody able to bind all histone H2A types, including H2AX, and γ-H2AX antibody able to bind only the phosphorylated form of H2AX (serine 139).

This H2A.X antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.

10 dagar pappa
chalmers studentbostäder andrahandsuthyrning

H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. An important phosphorylated form is γH2AX (140S), which forms when double-strand breaks appear.

Gamma H2AX (gammaH2AX) is the phosphorylated version of histone H2AX and is a marker for double-stranded breaks (DSBs) caused by DNA damage (1-4). H2AX is a variant of histone H2A, one of the histone core molecules forming the nucleosome, and is a vital component in repairing DNA damage (1-4). The H2AX variant represents between 2-25% of total H2A (1-3). gamma-H2AX Antibody, A300-081A. Rabbit anti-gamma-H2AX Antibody, Affinity Purified.